Response Surfaces - Merck Dataset

vs. in

Best-Fit BRAID Parameters

E₀			0.100
ID_M,A	0.100	ID_M,B	0.100
n_a	0.100	n_b	0.100
E_f,A	0.100	E_f,B	0.100
κ			0.100

Additional Metrics

V_Bliss
CI₅₀
IAE₅₀
R²

Drug A	Drug B	Cell Line

The specified surface was not found. It is possible that this combination of drugs was not tested in the specified cell line.

Shareable link to this response surface page:

stuff

O'Neil, J., Benita, Y., Feldman, I., et al. "An Unbiased Oncology Compound Screen to Identify Novel Combination Strategies." Molecular Cancer Therapeutics, 2016. 15(6): p. 1155-62.

Twarog, N.R., Stewart, E., Hammill, C.V., & Shelat, A.A. "BRAID: A Unifying Paradigm for the Analysis of Combined Drug Action." Scientific Reports, 2016, 6 p. 25523.